The Science Behind the HR23+ Formula
Why ingredient combinations matter in a comprehensive hair support supplement.
HR23+ was developed around a multi-ingredient approach to hair health, combining vitamins, minerals, amino acids and botanical extracts that have been studied for their potential role in supporting normal hair growth, scalp condition, follicle health and nutritional balance.
Research Summary
Rather than relying on one single ingredient, HR23+ brings together a broad range of nutrients and plant extracts that may support hair health from several angles, including nutritional support, oxidative stress, scalp condition, DHT-related pathways and hair structure.
This page explains the rationale behind several key ingredient groups used within the HR23+ formula. It is intended as an educational overview of the ingredient combinations, not as clinical proof that HR23+ treats or cures hair loss.
Part of the HR23+ Research & Evidence Centre
This article forms part of the wider HR23+ Hair Loss Research & Evidence Centre, which brings together customer outcomes, documented case studies, ingredient research and transparency updates.
Why HR23+ Uses a Multi-Ingredient Formula
Hair loss and thinning hair are rarely caused by one factor alone. Genetics, hormones, age, stress, nutrition, inflammation, scalp condition and lifestyle can all influence the hair growth cycle. This is why single-ingredient supplements often have limited value for many people.
The HR23+ formula was designed to support hair health across several areas at once. The aim is to combine complementary ingredients that may help support normal hair growth, stronger hair structure, healthier scalp conditions and improved nutritional support for the follicle environment.
DHT-Related Support
Saw palmetto, nettle leaf, pumpkin seed and grape seed extract are included for their use in natural formulas focused on DHT-related hair thinning.
Nutritional Support
Biotin, B vitamins, zinc, copper and folate help support normal hair, cell function, energy metabolism and overall nutritional balance.
Hair Structure
L-cysteine, MSM, silica and horsetail are included for their association with keratin, connective tissue and stronger hair structure.
Scalp Environment
Green tea, ginkgo biloba and grape seed extract provide antioxidant and circulation-focused support for the scalp and follicle environment.
Ingredient Focus: Saw Palmetto
Saw palmetto is one of the most widely used botanical extracts in natural hair loss supplements. It is commonly associated with androgenetic alopecia because of its potential relationship with 5-alpha-reductase, the enzyme involved in the conversion of testosterone into dihydrotestosterone, better known as DHT.
DHT is strongly linked with follicle miniaturisation in male and female pattern hair loss. For this reason, saw palmetto is often included in non-medical hair support formulas aimed at people experiencing early-stage thinning.
Research Highlight
Saw palmetto has been investigated for its potential role in DHT-related hair loss. While it should not be presented as equivalent to prescription medication, it remains one of the most recognised natural ingredients used in hair support formulas.
Why HR23+ Combines Saw Palmetto with Other Ingredients
Saw palmetto is not used in isolation within HR23+. It is combined with other ingredients that may complement its role in supporting hair health.
Saw Palmetto + Pumpkin Seed
Pumpkin seed extract contains phytosterols and other compounds commonly used in formulas focused on DHT-related support and scalp health.
Saw Palmetto + Zinc
Zinc contributes to the maintenance of normal hair and supports normal immune function, making it a useful mineral in hair health supplementation.
Saw Palmetto + Nettle Leaf
Nettle leaf is another botanical extract commonly used alongside saw palmetto in natural hair and scalp support formulas.
Ingredient Focus: Inositol & Choline
Inositol and choline are B-vitamin-like compounds often used together in nutritional formulas. They are not direct hair loss treatments, but they may contribute to overall metabolic balance, lipid metabolism, nervous system function and general wellbeing.
Their inclusion in HR23+ reflects a broader approach to hair support. Healthy hair growth depends not only on follicle activity, but also on the body's ability to maintain normal nutritional, metabolic and hormonal balance.
Research Highlight
Research specifically linking inositol and choline to hair regrowth is limited. However, both nutrients are relevant to wider metabolic and cellular health, which may indirectly support the conditions needed for healthy hair.
Why They Are Included Together
Choline and inositol are often paired because they both play roles in lipid metabolism and cellular function. In the context of hair health, this may be relevant to scalp condition, follicle environment and general nutritional support.
They are best viewed as supportive nutrients within a wider formula rather than stand-alone hair growth agents.
Ingredient Focus: Folate
Folate, also known as vitamin B9, supports normal cell division and contributes to normal blood formation. These functions are relevant to general hair health because hair follicles are among the most active tissues in the body.
While folate should not be described as a direct hair loss treatment, maintaining adequate folate levels is part of supporting normal biological processes that can influence hair quality and scalp health.
Folate + Zinc
Zinc contributes to the maintenance of normal hair. Folate supports normal cell division, making the combination relevant to general hair support.
Folate + Copper
Copper contributes to normal hair pigmentation and connective tissue health, while folate supports normal cellular function.
Folate + B Vitamins
Folate works alongside other B vitamins in many processes connected to energy metabolism, cell function and overall wellbeing.
Ingredient Focus: Ginkgo Biloba
Ginkgo biloba is a botanical extract best known for its association with circulation and antioxidant support. In hair health formulas, it is often included for its potential role in supporting the scalp environment.
Although ginkgo biloba is not a direct treatment for androgenetic alopecia, it may complement other nutrients by supporting general scalp condition and helping create a healthier environment for the hair follicle.
Ginkgo + Biotin
Biotin contributes to the maintenance of normal hair, while ginkgo is included for general scalp and circulation-focused support.
Ginkgo + Saw Palmetto
This pairing combines scalp-supporting botanical activity with ingredients commonly used in DHT-focused hair formulas.
Ginkgo + Zinc
Zinc supports normal hair maintenance, while ginkgo contributes broader antioxidant and scalp-supporting properties.
Ingredient Focus: Horsetail
Horsetail extract is naturally rich in silica, a trace mineral associated with hair strength, connective tissue support and overall hair quality. For this reason, horsetail is commonly included in hair, skin and nail supplements.
Hair is largely made from keratin, and ingredients that support the structure and resilience of hair fibres can be useful within a broader hair support formula.
Horsetail + MSM
MSM provides sulphur, which is associated with keratin structure. Horsetail contributes silica, making the combination relevant to hair strength.
Horsetail + Ginkgo
This pairing combines structural hair support with broader scalp and circulation-focused support.
Horsetail + Saw Palmetto
This combination supports two different areas: hair structure and DHT-related hair support.
Why Ingredient Combinations Matter
The main rationale behind HR23+ is that hair health usually requires support from several directions. A formula that only contains one popular ingredient may miss other important factors such as nutrition, scalp health, oxidative stress, hair fibre strength and hormonal influences.
By combining complementary ingredients, HR23+ aims to provide a wider foundation for healthier hair. This does not mean every user will experience the same results, but it does explain why the formula was developed as a 23-ingredient supplement rather than a basic single-nutrient product.
The HR23+ Formula Approach
1. Support the follicle environment through nutrients and botanical extracts associated with scalp health.
2. Support normal hair maintenance with recognised nutrients such as biotin, zinc and copper.
3. Support hair structure using ingredients associated with keratin, silica and connective tissue.
4. Support long-term consistency through a once-daily supplement routine designed for continued use.
Important Note on Evidence
Many ingredients used within HR23+ have been studied individually or used in nutritional and botanical formulas associated with hair health. However, this page should not be interpreted as claiming that HR23+ itself has been proven in an independent published clinical trial.
Current HR23+ evidence includes ingredient research, customer outcomes, documented case studies and long-term customer feedback collected since 2015. We remain committed to transparent product development and responsible communication.
Summary
HR23+ was developed around the idea that hair health is best supported through a broad, multi-ingredient formula rather than one isolated nutrient. The formula combines vitamins, minerals, amino acids and botanical extracts chosen for their potential roles in hair structure, nutritional support, scalp condition and DHT-related hair health.
While no supplement can guarantee results for every individual, the HR23+ formula reflects more than a decade of product development, ingredient research and real-world customer feedback. This ongoing evidence-led approach continues to shape how HR23+ is presented, reviewed and improved.