Grape seed extract is a very potent supplement that acts as an antiallergenic, antihistamine, anti-inflammatory, and antioxidant. Like Pygeum Africanum and Saw Palmetto, Grape Seed extract has also been found to inhibit DHT production, and thus prevent hair follicle damage.
The effectiveness of proanthocyanidins in hair regrowth is said to be similar to the drug, Minoxidil. Other follow-up studies have confirmed this doubling of the anagen phase and rapid hair growth caused by proanthocyanidins.
There are multiple possible ways by which grape seed extract promotes hair regrowth and reverses hair loss. The action of proanthocyanidins found in the grape seed extract plays a key role. It inhibits the conversion of testosterone to dihydrotestosterone (DHT). High levels of DHT are known to cause androgenic alopecia - grape seed extract can be used to reduce the rate of hair loss. Proanthocyanidins also act as growth stimulants for hair follicles.
An extensive hair study by Japanese researchers showed that proanthocyanidins extracted from grape seeds not only stopped hair loss but increased the growth of hair cells by over 200%. Proanthocyanidins generated two anagen, or hair growth phases. Instead of the telogen phase during which the hair growth cycle shows no activity, proanthocyanidins produced another anagen phase, a twin-peak that led to rapid hair regrowth.
Grape seed extract also promotes skin health, which contributes to hair growth. For example, the improved microcirculation in the capillaries close to the skin means that the cells of hair follicles are adequately perfused with nourishment and oxygen. This leads to the increased production of nitric oxide at these sites. Nitric oxide is a known vaso-relaxant which dilates the blood vessels improving blood circulation to the capillaries feeding skin cells and hair follicles.
Finally, there is the antioxidant property of grape seed extract which is rated above Vitamin C and E. By clearing away free radicals, grape seed extract provides anti-ageing benefits and protects the integrity of hair follicle cells from oxidative damage, giving hair strands a longer lifespan before falling off.